Rabbit Anti-T2R46/TAS2R46 Polyclonal Antibody
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产品编号
PAV3926
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别名
taste 2 receptor member 46, T2R46, T2R54
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | taste 2 receptor member 46, T2R46, T2R54 |
| Catalog Number | PAV3926 |
| Product Description | Rabbit polyclonal antibody raised against human TAS2R46 (Taste receptor type 2 member 46). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | TAS2R46 |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 其他受体 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | TAS2R46 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and mediate the perception of bitterness through a G protein-coupled second messenger pathway (Conte et al., 2002 [PubMed 12584440]). For further information on TAS2Rs, see MIM 604791.[supplied by OMIM, Sep 2009] |
| Immunogen | This antibody was raised against from part region of human TAS2R46 protein (UniProt: P59540) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 259292 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈35.5 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 35.5 kDa |
| Cross-reactivity | Human |
| Uniprot ID | P59540 |
| Note | Gene ID: 259292; UniProt: P59540; Chromosome: 12p13.2; Predicted MW: 35.5 kDa |
| Function | Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human TAS2R46 Polyclonal Antibody |
| Target | TAS2R46 |
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