Rabbit Anti-R4RL1/RTN4RL1 Polyclonal Antibody
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产品编号
PAV3230
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别名
reticulon 4 receptor like 1, NGRH2, NgR3
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | reticulon 4 receptor like 1, NGRH2, NgR3 |
| Catalog Number | PAV3230 |
| Product Description | Rabbit polyclonal antibody raised against human RTN4RL1 (Reticulon-4 receptor-like 1). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | RTN4RL1 |
| Species | Human, Rat, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 其他受体 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Enables signaling receptor activity. Predicted to be involved in negative regulation of axon regeneration and positive regulation of synapse assembly. Located in cell surface and plasma membrane. [provided by Alliance of Genome Resources, Jun 2026] |
| Immunogen | This antibody was raised against from part region of human RTN4RL1 protein (UniProt: Q86UN2) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 146760 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Rat, Mouse |
| Predicted Molecular Weight | ≈49.1 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 49.1 kDa |
| Cross-reactivity | Human, Rat, Mouse |
| Uniprot ID | Q86UN2 |
| Note | Gene ID: 146760; UniProt: Q86UN2; Chromosome: 17p13.3; Predicted MW: 49.1 kDa |
| Function | Cell surface receptor. Plays a functionally redundant role in postnatal brain development and in regulating axon regeneration in the adult central nervous system. Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum. Protects motoneurons against apoptosis; protection against apoptosis is probably mediated by MAG. Plays a role in inhibiting neurite outgrowth and axon regeneration via its binding to neuronal chondroitin sulfate proteoglycans. Binds heparin (By similarity). Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development. Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human RTN4RL1 Polyclonal Antibody |
| Target | RTN4RL1 |
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