Rabbit Anti-PLXA3/PLXNA3 Polyclonal Antibody
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产品编号
PAV3087
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别名
plexin A3, 6.3, HSSEXGENE, PLXN3, PLXN4, XAP-6
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | plexin A3, 6.3, HSSEXGENE, PLXN3, PLXN4, XAP-6 |
| Catalog Number | PAV3087 |
| Product Description | Rabbit polyclonal antibody raised against human PLXNA3 (Plexin-A3). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | PLXNA3 |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 其他受体 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a member of the plexin class of proteins. The encoded protein is a class 3 semaphorin receptor, and may be involved in cytoskeletal remodeling and as well as apoptosis. Studies of a similar gene in zebrafish suggest that it is important for axon pathfinding in the developing nervous system. This gene may be associated with tumor progression. [provided by RefSeq, Aug 2013] |
| Immunogen | This antibody was raised against from part region of human PLXNA3 protein (UniProt: P51805) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 55558 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈207.7 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 207.7 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | P51805 |
| Note | Gene ID: 55558; UniProt: P51805; Chromosome: Xq28; Predicted MW: 207.7 kDa |
| Function | Coreceptor for SEMA3A and SEMA3F. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Regulates the migration of sympathetic neurons, but not of neural crest precursors. Required for normal dendrite spine morphology in pyramidal neurons. May play a role in regulating semaphorin-mediated programmed cell death in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human PLXNA3 Polyclonal Antibody |
| Target | PLXNA3 |
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