Rabbit Anti-PHLP/PDCL Polyclonal Antibody
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产品编号
PAV3025
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别名
phosducin like, PhLP
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | phosducin like, PhLP |
| Catalog Number | PAV3025 |
| Product Description | Rabbit polyclonal antibody raised against human PDCL (Phosducin-like protein). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | PDCL |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 其他受体 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Phosducin-like protein is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin, a phosphoprotein expressed in retina and pineal gland. Both phosducin-like protein and phosphoducin have been shown to regulate G-protein signaling by binding to the beta-gamma subunits of G proteins. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human PDCL protein (UniProt: Q13371) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 5082 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈34.3 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 34.3 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | Q13371 |
| Note | Gene ID: 5082; UniProt: Q13371; Chromosome: 9q33.2; Predicted MW: 34.3 kDa |
| Function | Acts as a positive regulator of hedgehog signaling and regulates ciliary function.; FUNCTION: [Isoform 1]: Functions as a co-chaperone for CCT in the assembly of heterotrimeric G protein complexes, facilitates the assembly of both Gbeta-Ggamma and RGS-Gbeta5 heterodimers.; FUNCTION: [Isoform 2]: Acts as a negative regulator of heterotrimeric G proteins assembly by trapping the preloaded G beta subunits inside the CCT chaperonin. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human PDCL Polyclonal Antibody |
| Target | PDCL |
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