Rabbit Anti-PGRC1/PGRMC1 Polyclonal Antibody
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产品编号
PAV3013
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别名
progesterone receptor membrane component 1, Dap1, HPR6.6, IZA, MPR
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | progesterone receptor membrane component 1, Dap1, HPR6.6, IZA, MPR |
| Catalog Number | PAV3013 |
| Product Description | Rabbit polyclonal antibody raised against human PGRMC1 (Membrane-associated progesterone receptor component 1). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | PGRMC1 |
| Species | Human, Rat, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 其他受体 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a putative membrane-associated progesterone steroid receptor. The protein is expressed predominantly in the liver and kidney. [provided by RefSeq, Mar 2010] |
| Immunogen | This antibody was raised against from part region of human PGRMC1 protein (UniProt: O00264) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 10857 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Rat, Mouse |
| Predicted Molecular Weight | ≈21.7 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 21.7 kDa |
| Cross-reactivity | Human, Rat, Mouse |
| Uniprot ID | O00264 |
| Note | Gene ID: 10857; UniProt: O00264; Chromosome: Xq24; Predicted MW: 21.7 kDa |
| Function | Component of a progesterone-binding protein complex. Binds progesterone. Has many reported cellular functions (heme homeostasis, interaction with CYPs). Required for the maintenance of uterine histoarchitecture and normal female reproductive lifespan (By similarity). Intracellular heme chaperone. Regulates heme synthesis via interactions with FECH and acts as a heme donor for at least some hemoproteins. Forms a ternary complex with TMEM97 receptor and low density lipid receptor/LDLR, which increases LDLR-mediated LDL lipoprotein internalization. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human PGRMC1 Polyclonal Antibody |
| Target | PGRMC1 |
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