Rabbit Anti-MRAP Polyclonal Antibody
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产品编号
PAV2360
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别名
melanocortin 2 receptor accessory protein, B27, C21orf61, FALP, GCCD2, MRAP1
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | melanocortin 2 receptor accessory protein, B27, C21orf61, FALP, GCCD2, MRAP1 |
| Catalog Number | PAV2360 |
| Product Description | Rabbit polyclonal antibody raised against human MRAP (Melanocortin-2 receptor accessory protein). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | MRAP |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 其他受体 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a melanocortin receptor-interacting protein. The encoded protein regulates trafficking and function of the melanocortin 2 receptor in the adrenal gland. The encoded protein can also modulate signaling of other melanocortin receptors. Mutations in this gene have been associated with familial glucocorticoid deficiency type 2. Alternatively spliced transcript variants have been described. [provided by RefSeq, Dec 2009] |
| Immunogen | This antibody was raised against from part region of human MRAP protein (UniProt: Q8TCY5) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 56246 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈19.1 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 19.1 kDa |
| Cross-reactivity | Human |
| Uniprot ID | Q8TCY5 |
| Note | Gene ID: 56246; UniProt: Q8TCY5; Chromosome: 21q22.11; Predicted MW: 19.1 kDa |
| Function | Modulator of melanocortin receptors (MC1R, MC2R, MC3R, MC4R and MC5R). Acts by increasing ligand-sensitivity of melanocortin receptors and enhancing generation of cAMP by the receptors. Required both for MC2R trafficking to the cell surface of adrenal cells and for signaling in response to corticotropin (ACTH). May be involved in the intracellular trafficking pathways in adipocyte cells. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human MRAP Polyclonal Antibody |
| Target | MRAP |
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