Rabbit Anti-MPRD/M6PR Polyclonal Antibody
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产品编号
PAV2357
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别名
mannose-6-phosphate receptor, cation dependent, CD-M6PR, CD-MPR, MPR 46, MPR-46, MPR46, SMPR
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | mannose-6-phosphate receptor, cation dependent, CD-M6PR, CD-MPR, MPR 46, MPR-46, MPR46, SMPR |
| Catalog Number | PAV2357 |
| Product Description | Rabbit polyclonal antibody raised against human M6PR (Cation-dependent mannose-6-phosphate receptor). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | M6PR |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 其他受体 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, May 2011] |
| Immunogen | This antibody was raised against from part region of human M6PR protein (UniProt: P20645) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 4074 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈31.0 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 31.0 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | P20645 |
| Note | Gene ID: 4074; UniProt: P20645; Chromosome: 12p13.31; Predicted MW: 31.0 kDa |
| Function | Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human M6PR Polyclonal Antibody |
| Target | M6PR |
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