Rabbit Anti-MAL Polyclonal Antibody
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产品编号
PAV2233
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别名
TIR domain containing adaptor protein, BACTS1, Mal, MyD88-2, wyatt
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | TIR domain containing adaptor protein, BACTS1, Mal, MyD88-2, wyatt |
| Catalog Number | PAV2233 |
| Product Description | Rabbit polyclonal antibody raised against human TIRAP (Myelin and lymphocyte protein). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | TIRAP |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 其他免疫分子 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human TIRAP protein (UniProt: P21145) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 114609 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈16.7 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 16.7 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | P21145 |
| Note | Gene ID: 114609; UniProt: P21145; Chromosome: 11q24.2; Predicted MW: 16.7 kDa |
| Function | May be involved in vesicular trafficking from the Golgi apparatus to the cell membrane. Plays a role in the maintenance of the myelin sheath, and in axon-glia and glia-glia interactions. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human TIRAP Polyclonal Antibody |
| Target | TIRAP |
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