Rabbit Anti-TR150/THRAP3 Polyclonal Antibody
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产品编号
PAV4113
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别名
thyroid hormone receptor associated protein 3, BCLAF2, TRAP150
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | thyroid hormone receptor associated protein 3, BCLAF2, TRAP150 |
| Catalog Number | PAV4113 |
| Product Description | Rabbit polyclonal antibody raised against human THRAP3 (Thyroid hormone receptor-associated protein 3). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | THRAP3 |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 核受体 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Enables nuclear thyroid hormone receptor binding activity; phosphoprotein binding activity; and transcription coactivator activity. Involved in positive regulation of circadian rhythm and regulation of gene expression. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in exon-exon junction complex and nuclear speck. Part of mediator complex. [provided by Alliance of Genome Resources, Jul 2025] |
| Immunogen | This antibody was raised against from part region of human THRAP3 protein (UniProt: Q9Y2W1) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 9967 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈108.7 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 108.7 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | Q9Y2W1 |
| Note | Gene ID: 9967; UniProt: Q9Y2W1; Chromosome: 1p34.3; Predicted MW: 108.7 kDa |
| Function | Involved in pre-mRNA splicing. Remains associated with spliced mRNA after splicing which probably involves interactions with the exon junction complex (EJC). Can trigger mRNA decay which seems to be independent of nonsense-mediated decay involving premature stop codons (PTC) recognition. May be involved in nuclear mRNA decay. Involved in regulation of signal-induced alternative splicing. During splicing of PTPRC/CD45 is proposed to sequester phosphorylated SFPQ from PTPRC/CD45 pre-mRNA in resting T-cells. Involved in cyclin-D1/CCND1 mRNA stability probably by acting as component of the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. Involved in response to DNA damage. Is excluced from DNA damage sites in a manner that parallels transcription inhibition; the function may involve the SNARP complex. Initially thought to play a role in transcriptional coactivation through its association with the TRAP complex; however, it is not regarded as a stable Mediator complex subunit. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human THRAP3 Polyclonal Antibody |
| Target | THRAP3 |
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