Rabbit Anti-NR2E1 Polyclonal Antibody
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产品编号
PAV2594
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别名
nuclear receptor subfamily 2 group E member 1, TLL, TLX, XTLL
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | nuclear receptor subfamily 2 group E member 1, TLL, TLX, XTLL |
| Catalog Number | PAV2594 |
| Product Description | Rabbit polyclonal antibody raised against human NR2E1 (Nuclear receptor subfamily 2 group E member 1). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | NR2E1 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 核受体 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The protein encoded by this gene is an orphan receptor involved in retinal development. The encoded protein also regulates adult neural stem cell proliferation and may be involved in control of aggressive behavior. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015] |
| Immunogen | This antibody was raised against from part region of human NR2E1 protein (UniProt: Q9Y466) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 7101 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈42.6 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 42.6 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q9Y466 |
| Note | Gene ID: 7101; UniProt: Q9Y466; Chromosome: 6q21; Predicted MW: 42.6 kDa |
| Function | Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity (By similarity). May be required to pattern anterior brain differentiation. Involved in the regulation of retinal development and essential for vision. During retinogenesis, regulates PTEN-Cyclin D expression via binding to the promoter region of PTEN and suppressing its activity (By similarity). May be involved in retinoic acid receptor (RAR) regulation in retinal cells. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human NR2E1 Polyclonal Antibody |
| Target | NR2E1 |
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