Rabbit Anti-SV2B Polyclonal Antibody
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产品编号
PAV3881
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别名
synaptic vesicle glycoprotein 2B, HsT19680, SLC22B2
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | synaptic vesicle glycoprotein 2B, HsT19680, SLC22B2 |
| Catalog Number | PAV3881 |
| Product Description | Rabbit polyclonal antibody raised against human SV2B (Synaptic vesicle glycoprotein 2B). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | SV2B |
| Species | Human, Rat, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 神经元标记物 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a member of the synaptic vesicle proteins 2 (SV2) family and major facilitator superfamily of proteins. This protein and other members of the family are localized to synaptic vesicles and may function in the regulation of vesicle trafficking and exocytosis. Studies in mice suggest that the encoded protein may act as a protein receptor for botulinum neurotoxin E in neurons, and that this protein may be important for the integrity of the glomerular filtration barrier. This gene shows reduced expression in areas of synaptic loss in the hippocampus of human temporal lobe epilepsy patients. [provided by RefSeq, Sep 2016] |
| Immunogen | This antibody was raised against from part region of human SV2B protein (UniProt: Q7L1I2) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 9899 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Rat, Mouse |
| Predicted Molecular Weight | ≈77.4 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 77.4 kDa |
| Cross-reactivity | Human, Rat, Mouse |
| Uniprot ID | Q7L1I2 |
| Note | Gene ID: 9899; UniProt: Q7L1I2; Chromosome: 15q26.1; Predicted MW: 77.4 kDa |
| Function | Probably plays a role in the control of regulated secretion in neural and endocrine cells.; FUNCTION: (Microbial infection) Receptor for the C.botulinum neurotoxin type A2 (BoNT/A, botA); glycosylation is not essential but enhances the interaction. Probably also serves as a receptor for the closely related C.botulinum neurotoxin type A1. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human SV2B Polyclonal Antibody |
| Target | SV2B |
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