Rabbit Anti-TTC19 Polyclonal Antibody
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产品编号
PAV4175
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别名
tetratricopeptide repeat domain 19, 2010204O13Rik, MC3DN2
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | tetratricopeptide repeat domain 19, 2010204O13Rik, MC3DN2 |
| Catalog Number | PAV4175 |
| Product Description | Rabbit polyclonal antibody raised against human TTC19 (Tetratricopeptide repeat protein 19, mitochondrial). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | TTC19 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 线粒体蛋白 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a protein with a tetratricopeptide repeat (TPR) domain containing several TPRs of about 34 aa each. These repeats are found in a variety of organisms including bacteria, fungi and plants, and are involved in a variety of functions including protein-protein interactions. This protein is embedded in the inner mitochondrial membrane and is involved in the formation of the mitochondrial respiratory chain III. It has also been suggested that this protein plays a role in cytokinesis. Mutations in this gene cause mitochondrial complex III deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2012] |
| Immunogen | This antibody was raised against from part region of human TTC19 protein (UniProt: Q6DKK2) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 54902 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈42.5 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 42.5 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q6DKK2 |
| Note | Gene ID: 54902; UniProt: Q6DKK2; Chromosome: 17p12; Predicted MW: 42.5 kDa |
| Function | Required for the preservation of the structural and functional integrity of mitochondrial respiratory complex III by allowing the physiological turnover of the Rieske protein UQCRFS1. Involved in the clearance of UQCRFS1 N-terminal fragments, which are produced upon incorporation of UQCRFS1 into the complex III and whose presence is detrimental for its catalytic activity. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human TTC19 Polyclonal Antibody |
| Target | TTC19 |
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