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Rabbit Anti-TIM50/TIMM50 Polyclonal Antibody
Rabbit Anti-TIM50/TIMM50 Polyclonal Antibody

Rabbit Anti-TIM50/TIMM50 Polyclonal Antibody

产品编号

PAV4034

别名

translocase of inner mitochondrial membrane 50, MGCA9, TIM50, TIM50L

目录价格

InquiryRMB

规格
  • 100ul
产品介绍
Aliastranslocase of inner mitochondrial membrane 50, MGCA9, TIM50, TIM50L
Catalog NumberPAV4034
Product DescriptionRabbit polyclonal antibody raised against human TIMM50 (Mitochondrial import inner membrane translocase subunit TIM50). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular NameTIMM50
SpeciesHuman, Mouse
HostRabbit
Size100ul
ClonityPolyclonal
Protein Family线粒体蛋白
Concentration1 mg/ml
Purificationaffinity-chromatography
Formulationsupply in PBS containing 50% glycerol, and 0.02% sodium azide.
BackgroundThis gene encodes a subunit of the TIM23 inner mitochondrial membrane translocase complex. The encoded protein functions as the receptor subunit that recognizes the mitochondrial targeting signal, or presequence, on protein cargo that is destined for the mitochondrial inner membrane and matrix. This protein may also play a role in maintaining the membrane permeability barrier, and knockdown of this gene in human cells results in the release of cytochrome c and apoptosis. [provided by RefSeq, Jul 2016]
ImmunogenThis antibody was raised against from part region of human TIMM50 protein (UniProt: Q3ZCQ8)
ApplicationWB
Recommended DilutionWB 1:500-2000
Gene ID92609
TagUnconjugated
Cross-reactivityHuman, Mouse
Predicted Molecular Weight≈39.6 kDa
Storage ConditionStore at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping ConditionThis product is shipped on blue ice.
Molecular Weight39.6 kDa
Cross-reactivityHuman, Mouse
Uniprot IDQ3ZCQ8
NoteGene ID: 92609; UniProt: Q3ZCQ8; Chromosome: 19q13.2; Predicted MW: 39.6 kDa
FunctionEssential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo.; FUNCTION: [Isoform 2]: May participate in the release of snRNPs and SMN from the Cajal body.
Product Declaration本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full NameRabbit Anti-Human TIMM50 Polyclonal Antibody
TargetTIMM50

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