Rabbit Anti-NDUS2/NDUFS2 Polyclonal Antibody
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产品编号
PAV2490
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别名
NADH:ubiquinone oxidoreductase core subunit S2, CI-49, LHONAR2, MC1DN6
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | NADH:ubiquinone oxidoreductase core subunit S2, CI-49, LHONAR2, MC1DN6 |
| Catalog Number | PAV2490 |
| Product Description | Rabbit polyclonal antibody raised against human NDUFS2 (NADH dehydrogenase iron-sulfur protein 2, mitochondrial). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | NDUFS2 |
| Species | Human, Rat, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 线粒体蛋白 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009] |
| Immunogen | This antibody was raised against from part region of human NDUFS2 protein (UniProt: O75306) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 4720 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Rat, Mouse |
| Predicted Molecular Weight | ≈52.5 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 52.5 kDa |
| Cross-reactivity | Human, Rat, Mouse |
| Uniprot ID | O75306 |
| Note | Gene ID: 4720; UniProt: O75306; Chromosome: 1q23.3; Predicted MW: 52.5 kDa |
| Function | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I. Essential for the assembly of complex I (By similarity). Redox-sensitive, critical component of the oxygen-sensing pathway in the pulmonary vasculature which plays a key role in acute pulmonary oxygen-sensing and hypoxic pulmonary vasoconstriction. Plays an important role in carotid body sensing of hypoxia (By similarity). Essential for glia-like neural stem and progenitor cell proliferation, differentiation and subsequent oligodendrocyte or neuronal maturation (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human NDUFS2 Polyclonal Antibody |
| Target | NDUFS2 |
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