Rabbit Anti-NDUAD/NDUFA13 Polyclonal Antibody
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产品编号
PAV2482
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别名
NADH:ubiquinone oxidoreductase subunit A13, B16.6, CDA016, CGI-39, GRIM-19, GRIM19, MC1DN28
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | NADH:ubiquinone oxidoreductase subunit A13, B16.6, CDA016, CGI-39, GRIM-19, GRIM19, MC1DN28 |
| Catalog Number | PAV2482 |
| Product Description | Rabbit polyclonal antibody raised against human NDUFA13 (NADH dehydrogenase 1 alpha subcomplex subunit 13). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | NDUFA13 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 线粒体蛋白 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain. The protein is required for complex I assembly and electron transfer activity. The protein binds the signal transducers and activators of transcription 3 (STAT3) transcription factor, and can function as a tumor suppressor. The human protein purified from mitochondria migrates at approximately 16 kDa. Transcripts originating from an upstream promoter and capable of expressing a protein with a longer N-terminus have been found, but their biological validity has not been determined. [provided by RefSeq, Oct 2009] |
| Immunogen | This antibody was raised against from part region of human NDUFA13 protein (UniProt: Q9P0J0) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 51079 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈16.7 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 16.7 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q9P0J0 |
| Note | Gene ID: 51079; UniProt: Q9P0J0; Chromosome: 19p13.11; Predicted MW: 16.7 kDa |
| Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. Prevents the transactivation of STAT3 target genes. May play a role in CARD15-mediated innate mucosal responses and serve to regulate intestinal epithelial cell responses to microbes. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human NDUFA13 Polyclonal Antibody |
| Target | NDUFA13 |
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