Rabbit Anti-TMTC2 Polyclonal Antibody
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产品编号
PAV4077
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别名
transmembrane O-mannosyltransferase targeting cadherins 2, IBDBP1
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | transmembrane O-mannosyltransferase targeting cadherins 2, IBDBP1 |
| Catalog Number | PAV4077 |
| Product Description | Rabbit polyclonal antibody raised against human TMTC2 (Protein O-mannosyl-transferase TMTC2). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | TMTC2 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 代谢酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The protein encoded by this gene is an integral membrane protein localized to the endoplasmic reticulum (ER). The encoded protein contains many tetratricopeptide repeats, sequences known for being involved in protein-protein interactions. This protein binds both the calcium uptake pump SERCA2B and the carbohydrate-binding chaperone calnexin, and it appears to play a role in calcium homeostasis in the ER. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016] |
| Immunogen | This antibody was raised against from part region of human TMTC2 protein (UniProt: Q8N394) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 160335 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈94.1 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 94.1 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q8N394 |
| Note | Gene ID: 160335; UniProt: Q8N394; Chromosome: 12q21.31; Predicted MW: 94.1 kDa |
| Function | Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O-mannosyl-transferase on other proteins such as PDIA3. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human TMTC2 Polyclonal Antibody |
| Target | TMTC2 |
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