Rabbit Anti-TMM8A/PGAP6 Polyclonal Antibody
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产品编号
PAV4072
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别名
post-GPI attachment to proteins 6, GPI-PLA2, M83, TMEM6, TMEM8, TMEM8A
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | post-GPI attachment to proteins 6, GPI-PLA2, M83, TMEM6, TMEM8, TMEM8A |
| Catalog Number | PAV4072 |
| Product Description | Rabbit polyclonal antibody raised against human PGAP6 (Post-GPI attachment to proteins factor 6). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | PGAP6 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 代谢酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Predicted to enable A2-type glycerophospholipase activity. Predicted to be involved in lipid metabolic process. Located in nucleoplasm. [provided by Alliance of Genome Resources, Jun 2026] |
| Immunogen | This antibody was raised against from part region of human PGAP6 protein (UniProt: Q9HCN3) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 58986 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈84.8 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 84.8 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q9HCN3 |
| Note | Gene ID: 58986; UniProt: Q9HCN3; Chromosome: 16p13.3; Predicted MW: 84.8 kDa |
| Function | Involved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchor proteins (GPI-AP). Has phospholipase A2 activity that removes an acyl-chain at the sn-2 position of GPI-anchors during the remodeling of GPI. Required for the shedding of the GPI-AP CRIPTO, but not CFC1, at the cell surface. Shedding of CRIPTO modulates Nodal signaling by allowing soluble CRIPTO to act as a Nodal coreceptor on other cells. Also indirectly involved in the translocation of RAC1 from the cytosol to the plasma membrane by maintaining the steady state amount of CAV1-enriched plasma membrane subdomains, stabilizing RAC1 at the plasma membrane. In contrast to myomaker (TMEM8C), has no fusogenic activity. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human PGAP6 Polyclonal Antibody |
| Target | PGAP6 |
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