Rabbit Anti-THNS2/THNSL2 Polyclonal Antibody
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产品编号
PAV4019
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别名
threonine synthase like 2, SOFAT, THS2, TSH2
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | threonine synthase like 2, SOFAT, THS2, TSH2 |
| Catalog Number | PAV4019 |
| Product Description | Rabbit polyclonal antibody raised against human THNSL2 (Threonine synthase-like 2). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | THNSL2 |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 代谢酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a threonine synthase-like protein. A similar enzyme in mouse can catalyze the degradation of O-phospho-homoserine to a-ketobutyrate, phosphate, and ammonia. This protein also has phospho-lyase activity on both gamma and beta phosphorylated substrates. In mouse an alternatively spliced form of this protein has been shown to act as a cytokine and can induce the production of the inflammatory cytokine IL6 in osteoblasts. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011] |
| Immunogen | This antibody was raised against from part region of human THNSL2 protein (UniProt: Q86YJ6) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 55258 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈54.1 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 54.1 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | Q86YJ6 |
| Note | Gene ID: 55258; UniProt: Q86YJ6; Chromosome: 2p11.2; Predicted MW: 54.1 kDa |
| Function | [Isoform 1]: Acts as a catabolic phospho-lyase on both gamma- and beta-phosphorylated substrates. Degrades O-phospho-threonine (PThr) to alpha-ketobutyrate, ammonia and phosphate (By similarity).; FUNCTION: [Isoform SOFAT]: Potent inducer of osteoblastic production of IL6. May act to exacerbate inflammation and/or bone turnover under inflammatory conditions. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human THNSL2 Polyclonal Antibody |
| Target | THNSL2 |
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