Rabbit Anti-TDGF1 Polyclonal Antibody
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产品编号
PAV3992
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别名
cripto, EGF-CFC family member, CR, CR-1, CRGF, TDGF1
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | cripto, EGF-CFC family member, CR, CR-1, CRGF, TDGF1 |
| Catalog Number | PAV3992 |
| Product Description | Rabbit polyclonal antibody raised against human CRIPTO (Protein Cripto). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | CRIPTO |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 代谢酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010] |
| Immunogen | This antibody was raised against from part region of human CRIPTO protein (UniProt: P13385) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 6997 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈21.2 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 21.2 kDa |
| Cross-reactivity | Human |
| Uniprot ID | P13385 |
| Note | Gene ID: 6997; UniProt: P13385; Chromosome: 3p21.31; Predicted MW: 21.2 kDa |
| Function | GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated CRIPTO acts as a Nodal coreceptor in cis. Shedding of CRIPTO by TMEM8A modulates Nodal signaling by allowing soluble CRIPTO to act as a Nodal coreceptor on other cells. Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human CRIPTO Polyclonal Antibody |
| Target | CRIPTO |
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