Rabbit Anti-ST2A1/SULT2A1 Polyclonal Antibody
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产品编号
PAV3837
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别名
sulfotransferase family 2A member 1, DHEA-ST, DHEA-ST8, DHEAS, HST, ST2, ST2A1, ST2A3, STD
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | sulfotransferase family 2A member 1, DHEA-ST, DHEA-ST8, DHEAS, HST, ST2, ST2A1, ST2A3, STD |
| Catalog Number | PAV3837 |
| Product Description | Rabbit polyclonal antibody raised against human SULT2A1 (Sulfotransferase 2A1). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | SULT2A1 |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 代谢酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a member of the sulfotransferase family. Sulfotransferases aid in the metabolism of drugs and endogenous compounds by converting these substances into more hydrophilic water-soluble sulfate conjugates that can be easily excreted. This protein catalyzes the sulfation of steroids and bile acids in the liver and adrenal glands, and may have a role in the inherited adrenal androgen excess in women with polycystic ovary syndrome. [provided by RefSeq, Mar 2010] |
| Immunogen | This antibody was raised against from part region of human SULT2A1 protein (UniProt: Q06520) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 6822 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈33.8 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 33.8 kDa |
| Cross-reactivity | Human |
| Uniprot ID | Q06520 |
| Note | Gene ID: 6822; UniProt: Q06520; Chromosome: 19q13.33; Predicted MW: 33.8 kDa |
| Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands. Mediates the sulfation of a wide range of steroids and sterols, including pregnenolone, androsterone, DHEA, bile acids, cholesterol and as well many xenobiotics that contain alcohol and phenol functional groups. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Plays an important role in maintening steroid and lipid homeostasis. Plays a key role in bile acid metabolism, mediating formation of 3-sulfated bile acids. In addition, catalyzes the metabolic activation of potent carcinogenic polycyclic arylmethanols (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human SULT2A1 Polyclonal Antibody |
| Target | SULT2A1 |
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