Rabbit Anti-SOAT1 Polyclonal Antibody
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产品编号
PAV3743
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别名
sterol O-acyltransferase 1, ACACT, ACAT, ACAT-1, ACAT1, SOAT, STAT
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | sterol O-acyltransferase 1, ACACT, ACAT, ACAT-1, ACAT1, SOAT, STAT |
| Catalog Number | PAV3743 |
| Product Description | Rabbit polyclonal antibody raised against human SOAT1 (Sterol O-acyltransferase 1). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | SOAT1 |
| Species | Human, Rat, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 代谢酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The protein encoded by this gene belongs to the acyltransferase family. It is located in the endoplasmic reticulum, and catalyzes the formation of fatty acid-cholesterol esters. This gene has been implicated in the formation of beta-amyloid and atherosclerotic plaques by controlling the equilibrium between free cholesterol and cytoplasmic cholesteryl esters. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011] |
| Immunogen | This antibody was raised against from part region of human SOAT1 protein (UniProt: P35610) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 6646 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Rat, Mouse |
| Predicted Molecular Weight | ≈64.7 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 64.7 kDa |
| Cross-reactivity | Human, Rat, Mouse |
| Uniprot ID | P35610 |
| Note | Gene ID: 6646; UniProt: P35610; Chromosome: 1q25.2; Predicted MW: 64.7 kDa |
| Function | Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol. Plays a role in lipoprotein assembly and dietary cholesterol absorption. Preferentially utilizes oleoyl-CoA ((9Z)-octadecenoyl-CoA) as a substrate: shows a higher activity towards an acyl-CoA substrate with a double bond at the delta-9 position (9Z) than towards saturated acyl-CoA or an unsaturated acyl-CoA with a double bond at the delta-7 (7Z) or delta-11 (11Z) positions. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human SOAT1 Polyclonal Antibody |
| Target | SOAT1 |
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