Rabbit Anti-SIA8B/ST8SIA2 Polyclonal Antibody
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产品编号
PAV3673
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别名
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2, HsT19690, SIAT8-B, SIAT8B, ST8SIA-II, ST8SiaII, STX
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2, HsT19690, SIAT8-B, SIAT8B, ST8SIA-II, ST8SiaII, STX |
| Catalog Number | PAV3673 |
| Product Description | Rabbit polyclonal antibody raised against human ST8SIA2 (Alpha-2,8-sialyltransferase 8B). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | ST8SIA2 |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 代谢酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The protein encoded by this gene is a type II membrane protein that is thought to catalyze the transfer of sialic acid from CMP-sialic acid to N-linked oligosaccharides and glycoproteins. The encoded protein may be found in the Golgi apparatus and may be involved in the production of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). This protein is a member of glycosyltransferase family 29. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human ST8SIA2 protein (UniProt: Q92186) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 8128 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈42.4 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 42.4 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | Q92186 |
| Note | Gene ID: 8128; UniProt: Q92186; Chromosome: 15q26.1; Predicted MW: 42.4 kDa |
| Function | Catalyzes the transfer of a sialic acid from a CMP-linked sialic acid donor onto a terminal alpha-2,3-, alpha-2,6-, or alpha-2,8-linked sialic acid of an N-linked glycan acceptor through alpha-2,8-linkages (Probable). Therefore, participates in polysialic acid synthesis on various sialylated N-acetyllactosaminyl oligosaccharides (alpha-2,3-, alpha-2,6-, or alpha-2,8-linked sialic acid), including NCAM1, NCAM1 N-glycans, FETUB N-glycans, and to a lesser extent sialylparagloboside (SPG) and AHSG, which does not require the initial addition of an alpha 2,8-sialic acid (Probable). However, does not exhibit sialic acid-polymerase activity (By similarity). Catalyzes polysialic acid synthesis in the hippocampal on NCAM1 and supports neurite outgrowth. ST8SIA2-mediated polysialylation influences on oligodendrocyte differentiation and may promote the integrity of myelin and axons (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human ST8SIA2 Polyclonal Antibody |
| Target | ST8SIA2 |
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