Rabbit Anti-PREX1 Polyclonal Antibody
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产品编号
PAV3153
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别名
phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1, P-REX1
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1, P-REX1 |
| Catalog Number | PAV3153 |
| Product Description | Rabbit polyclonal antibody raised against human PREX1 (Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein-dependent Rac exchanger 1)). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | PREX1 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 代谢酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human PREX1 protein (UniProt: Q8TCU6) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 57580 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈186.2 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 186.2 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q8TCU6 |
| Note | Gene ID: 57580; UniProt: Q8TCU6; Chromosome: 20q13.13; Predicted MW: 186.2 kDa |
| Function | Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human PREX1 Polyclonal Antibody |
| Target | PREX1 |
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