Rabbit Anti-PMVK Polyclonal Antibody
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产品编号
PAV3092
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别名
phosphomevalonate kinase, HUMPMKI, PMK, PMKA, PMKASE, POROK1
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | phosphomevalonate kinase, HUMPMKI, PMK, PMKA, PMKASE, POROK1 |
| Catalog Number | PAV3092 |
| Product Description | Rabbit polyclonal antibody raised against human PMVK (Phosphomevalonate kinase). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | PMVK |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 代谢酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a peroxisomal enzyme that is a member of the galactokinase, homoserine kinase, mevalonate kinase, and phosphomevalonate kinase (GHMP) family of ATP-dependent enzymes. The encoded protein catalyzes the conversion of mevalonate 5-phosphate to mevalonate 5-diphosphate, which is the fifth step in the mevalonate pathway of isoprenoid biosynthesis. Mutations in this gene are linked to certain types of porokeratosis including disseminated superficial porokeratosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017] |
| Immunogen | This antibody was raised against from part region of human PMVK protein (UniProt: Q15126) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 10654 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈22.0 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 22.0 kDa |
| Cross-reactivity | Human |
| Uniprot ID | Q15126 |
| Note | Gene ID: 10654; UniProt: Q15126; Chromosome: 1q21.3; Predicted MW: 22.0 kDa |
| Function | Catalyzes the reversible ATP-dependent phosphorylation of mevalonate 5-phosphate to produce mevalonate diphosphate and ADP, a key step in the mevalonic acid mediated biosynthesis of isopentenyl diphosphate and other polyisoprenoid metabolites. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human PMVK Polyclonal Antibody |
| Target | PMVK |
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