Rabbit Anti-PLIN5 Polyclonal Antibody
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产品编号
PAV3076
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别名
perilipin 5, LSDA5, LSDP5, MLDP, OXPAT
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | perilipin 5, LSDA5, LSDP5, MLDP, OXPAT |
| Catalog Number | PAV3076 |
| Product Description | Rabbit polyclonal antibody raised against human PLIN5 (Perilipin-5). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | PLIN5 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 代谢酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Predicted to enable identical protein binding activity and lipase binding activity. Predicted to be involved in several processes, including negative regulation of peroxisome proliferator activated receptor signaling pathway; positive regulation of triglyceride storage; and regulation of lipid metabolic process. Predicted to act upstream of or within several processes, including cell activation; intracellular signaling cassette; and lipid droplet formation. Located in lipid droplet. [provided by Alliance of Genome Resources, Jun 2026] |
| Immunogen | This antibody was raised against from part region of human PLIN5 protein (UniProt: Q00G26) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 440503 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈50.8 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 50.8 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q00G26 |
| Note | Gene ID: 440503; UniProt: Q00G26; Chromosome: 19p13.3; Predicted MW: 50.8 kDa |
| Function | Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues. Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation. In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE. Reduces the triacylglycerol hydrolase activity of PNPLA2 by recruiting and sequestering PNPLA2 to lipid droplets. Phosphorylation by PKA enables lipolysis probably by promoting release of ABHD5 from the perilipin scaffold and by facilitating interaction of ABHD5 with PNPLA2. Also increases lipolysis through interaction with LIPE and upon PKA-mediated phosphorylation of LIPE (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human PLIN5 Polyclonal Antibody |
| Target | PLIN5 |
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