Rabbit Anti-PLCD1 Polyclonal Antibody
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产品编号
PAV3067
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别名
phospholipase C delta 1, NDNC3, PLC-III
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | phospholipase C delta 1, NDNC3, PLC-III |
| Catalog Number | PAV3067 |
| Product Description | Rabbit polyclonal antibody raised against human PLCD1 (1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | PLCD1 |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 代谢酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3). The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
| Immunogen | This antibody was raised against from part region of human PLCD1 protein (UniProt: P51178) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 5333 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈85.7 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 85.7 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | P51178 |
| Note | Gene ID: 5333; UniProt: P51178; Chromosome: 3p22.2; Predicted MW: 85.7 kDa |
| Function | The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. Essential for trophoblast and placental development (By similarity). Binds phosphatidylinositol 4,5-bisphosphate. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human PLCD1 Polyclonal Antibody |
| Target | PLCD1 |
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