Rabbit Anti-PDE5A Polyclonal Antibody
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产品编号
PAV2986
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别名
phosphodiesterase 5A, CGB-PDE, CN5A, PDE5
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | phosphodiesterase 5A, CGB-PDE, CN5A, PDE5 |
| Catalog Number | PAV2986 |
| Product Description | Rabbit polyclonal antibody raised against human PDE5A (cGMP-specific 3',5'-cyclic phosphodiesterase). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | PDE5A |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 代谢酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human PDE5A protein (UniProt: O76074) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 8654 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈100.0 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 100.0 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | O76074 |
| Note | Gene ID: 8654; UniProt: O76074; Chromosome: 4q26; Predicted MW: 100.0 kDa |
| Function | Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP. Specifically regulates nitric-oxide-generated cGMP. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human PDE5A Polyclonal Antibody |
| Target | PDE5A |
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