Rabbit Anti-PDE4B Polyclonal Antibody
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产品编号
PAV2985
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别名
phosphodiesterase 4B, DPDE4, PDEIVB
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | phosphodiesterase 4B, DPDE4, PDEIVB |
| Catalog Number | PAV2985 |
| Product Description | Rabbit polyclonal antibody raised against human PDE4B (3',5'-cyclic-AMP phosphodiesterase 4B). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | PDE4B |
| Species | Human, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 代谢酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014] |
| Immunogen | This antibody was raised against from part region of human PDE4B protein (UniProt: Q07343) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 5142 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Rat |
| Predicted Molecular Weight | ≈83.3 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 83.3 kDa |
| Cross-reactivity | Human, Rat |
| Uniprot ID | Q07343 |
| Note | Gene ID: 5142; UniProt: Q07343; Chromosome: 1p31.3; Predicted MW: 83.3 kDa |
| Function | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human PDE4B Polyclonal Antibody |
| Target | PDE4B |
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