Rabbit Anti-PDE1A Polyclonal Antibody
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产品编号
PAV2980
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别名
phosphodiesterase 1A, CAM-PDE 1A, CAM-PDE-1A, HCAM-1, HCAM1, HSPDE1A
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | phosphodiesterase 1A, CAM-PDE 1A, CAM-PDE-1A, HCAM-1, HCAM1, HSPDE1A |
| Catalog Number | PAV2980 |
| Product Description | Rabbit polyclonal antibody raised against human PDE1A (Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | PDE1A |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 代谢酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]).[supplied by OMIM, Oct 2009] |
| Immunogen | This antibody was raised against from part region of human PDE1A protein (UniProt: P54750) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 5136 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈61.3 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 61.3 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | P54750 |
| Note | Gene ID: 5136; UniProt: P54750; Chromosome: 2q32.1; Predicted MW: 61.3 kDa |
| Function | Calcium/calmodulin-dependent cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cGMP and cAMP, which are key regulators of many important physiological processes. Has a higher efficiency with cGMP compared to cAMP. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human PDE1A Polyclonal Antibody |
| Target | PDE1A |
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