Rabbit Anti-PANK4 Polyclonal Antibody
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产品编号
PAV2922
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别名
pantothenate kinase 4 (inactive), CTRCT49
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | pantothenate kinase 4 (inactive), CTRCT49 |
| Catalog Number | PAV2922 |
| Product Description | Rabbit polyclonal antibody raised against human PANK4 (4'-phosphopantetheine phosphatase). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | PANK4 |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 代谢酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is most abundant in muscle but is expressed in all tissues. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human PANK4 protein (UniProt: Q9NVE7) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 55229 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈86.0 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 86.0 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | Q9NVE7 |
| Note | Gene ID: 55229; UniProt: Q9NVE7; Chromosome: 1p36.32; Predicted MW: 86.0 kDa |
| Function | Phosphatase which shows a preference for 4'-phosphopantetheine and its oxidatively damaged forms (sulfonate or S-sulfonate), providing strong indirect evidence that the phosphatase activity pre-empts damage in the coenzyme A (CoA) pathway. Hydrolyzing excess 4'-phosphopantetheine could constitute a directed overflow mechanism to prevent its oxidation to the S-sulfonate, sulfonate, or other forms. Hydrolyzing 4'-phosphopantetheine sulfonate or S-sulfonate would forestall their conversion to inactive forms of CoA and acyl carrier protein. May play a role in the physiological regulation of CoA intracellular levels (Probable). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human PANK4 Polyclonal Antibody |
| Target | PANK4 |
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