Rabbit Anti-OSBP2 Polyclonal Antibody
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产品编号
PAV2867
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别名
oxysterol binding protein 2, HLM, ORP-4, ORP2, ORP4, OSBPL1, OSBPL4
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目录价格
InquiryRMB
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规格
- 100ul
| Alias | oxysterol binding protein 2, HLM, ORP-4, ORP2, ORP4, OSBPL1, OSBPL4 |
| Catalog Number | PAV2867 |
| Product Description | Rabbit polyclonal antibody raised against human OSBP2 (Oxysterol-binding protein 2). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | OSBP2 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 代谢酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The protein encoded by this gene contains a pleckstrin homology (PH) domain and an oxysterol-binding region. It binds oxysterols such as 7-ketocholesterol and may inhibit their cytotoxicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2013] |
| Immunogen | This antibody was raised against from part region of human OSBP2 protein (UniProt: Q969R2) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 23762 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈101.3 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 101.3 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q969R2 |
| Note | Gene ID: 23762; UniProt: Q969R2; Chromosome: 22q12.2; Predicted MW: 101.3 kDa |
| Function | Mediates the bidirectional lipid exchange between intracellular compartments and the plasma membrane, delivering cholesterol to the plasma membrane while transferring PI(4,5)P(2) to internal organelles, thereby modulating membrane lipid composition and associated signaling pathways. Binds 7-ketocholesterol. Acts during spermatid development where its function is required prior to the removal of cytoplasm from the sperm head (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human OSBP2 Polyclonal Antibody |
| Target | OSBP2 |
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