Rabbit Anti-OSBL6/OSBPL6 Polyclonal Antibody

产品编号

PAV2865

别名

oxysterol binding protein like 6, ORP6

目录价格

InquiryRMB

规格

100ul

DATASHEET COA

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产品介绍

Alias	oxysterol binding protein like 6, ORP6
Catalog Number	PAV2865
Product Description	Rabbit polyclonal antibody raised against human OSBPL6 (Oxysterol-binding protein-related protein 6). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular Name	OSBPL6
Species	Human, Mouse
Host	Rabbit
Size	100ul
Clonity	Polyclonal
Protein Family	代谢酶
Concentration	1 mg/ml
Purification	affinity-chromatography
Formulation	supply in PBS containing 50% glycerol, and 0.02% sodium azide.
Background	This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Immunogen	This antibody was raised against from part region of human OSBPL6 protein (UniProt: Q9BZF3)
Application	WB, ELISA
Recommended Dilution	WB 1:500-2000 ELISA 1:5000-20000
Gene ID	114880
Tag	Unconjugated
Cross-reactivity	Human, Mouse
Predicted Molecular Weight	≈106.3 kDa
Storage Condition	Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping Condition	This product is shipped on blue ice.
Molecular Weight	106.3 kDa
Cross-reactivity	Human, Mouse
Uniprot ID	Q9BZF3
Note	Gene ID: 114880; UniProt: Q9BZF3; Chromosome: 2q31.2; Predicted MW: 106.3 kDa
Function	Regulates cellular transport and efflux of cholesterol. Plays a role in phosphatidylinositol-4-phosphate (PI4P) turnover at the neuronal membrane. Localizes at the neurons plasma membrane-endoplasmic reticulum contact sites, and exchanges phosphatidylserine (1,2-diacyl-sn-glycero-3-phospho-L-serine, PS) from the endoplasmic reticulum for phosphatidylinositol-4-phosphate (1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate), PI(4)P) from the plasma membrane (By similarity). Binds via its PH domain PI4P, phosphatidylinositol-4,5-diphosphate, phosphatidylinositol-3,4,5-triphosphate, and phosphatidic acid (By similarity). Weakly binds 25-hydroxycholesterol.
Product Declaration	本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full Name	Rabbit Anti-Human OSBPL6 Polyclonal Antibody
Target	OSBPL6