Rabbit Anti-OSBL1/OSBPL1A Polyclonal Antibody
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产品编号
PAV2864
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别名
oxysterol binding protein like 1A, ORP-1, ORP1, OSBPL1B
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | oxysterol binding protein like 1A, ORP-1, ORP1, OSBPL1B |
| Catalog Number | PAV2864 |
| Product Description | Rabbit polyclonal antibody raised against human OSBPL1A (Oxysterol-binding protein-related protein 1). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | OSBPL1A |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 代谢酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Transcript variants derived from alternative promoter usage and/or alternative splicing exist; they encode different isoforms. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human OSBPL1A protein (UniProt: Q9BXW6) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 114876 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈108.5 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 108.5 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | Q9BXW6 |
| Note | Gene ID: 114876; UniProt: Q9BXW6; Chromosome: 18q11.2; Predicted MW: 108.5 kDa |
| Function | Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate (By similarity). Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A. Binds 25-hydroxycholesterol and cholesterol. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human OSBPL1A Polyclonal Antibody |
| Target | OSBPL1A |
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