Rabbit Anti-MYOF Polyclonal Antibody

产品编号

PAV2434

别名

myoferlin, FER1L3, HAE7

目录价格

InquiryRMB

规格

100ul

DATASHEET COA

立即询价加入询价列表大包装定制

产品介绍

Alias	myoferlin, FER1L3, HAE7
Catalog Number	PAV2434
Product Description	Rabbit polyclonal antibody raised against human MYOF (Myoferlin). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular Name	MYOF
Species	Human, Mouse
Host	Rabbit
Size	100ul
Clonity	Polyclonal
Protein Family	代谢酶
Concentration	1 mg/ml
Purification	affinity-chromatography
Formulation	supply in PBS containing 50% glycerol, and 0.02% sodium azide.
Background	Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined. [provided by RefSeq, Dec 2008]
Immunogen	This antibody was raised against from part region of human MYOF protein (UniProt: Q9NZM1)
Application	WB
Recommended Dilution	WB 1:500-2000
Gene ID	26509
Tag	Unconjugated
Cross-reactivity	Human, Mouse
Predicted Molecular Weight	≈234.7 kDa
Storage Condition	Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping Condition	This product is shipped on blue ice.
Molecular Weight	234.7 kDa
Cross-reactivity	Human, Mouse
Uniprot ID	Q9NZM1
Note	Gene ID: 26509; UniProt: Q9NZM1; Chromosome: 10q23.33; Predicted MW: 234.7 kDa
Function	Calcium/phospholipid-binding protein that plays a role in the plasmalemma repair mechanism of endothelial cells that permits rapid resealing of membranes disrupted by mechanical stress. Involved in endocytic recycling. Implicated in VEGF signal transduction by regulating the levels of the receptor KDR (By similarity).
Product Declaration	本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full Name	Rabbit Anti-Human MYOF Polyclonal Antibody
Target	MYOF