Rabbit Anti-TRPV5 Polyclonal Antibody
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产品编号
PAV4148
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别名
transient receptor potential cation channel subfamily V member 5, CAT2, ECAC1, OTRPC3
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | transient receptor potential cation channel subfamily V member 5, CAT2, ECAC1, OTRPC3 |
| Catalog Number | PAV4148 |
| Product Description | Rabbit polyclonal antibody raised against human TRPV5 (Transient receptor potential cation channel subfamily V member 5). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | TRPV5 |
| Species | Human, Rat, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 离子通道 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human TRPV5 protein (UniProt: Q9NQA5) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 56302 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Rat, Mouse |
| Predicted Molecular Weight | ≈82.6 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 82.6 kDa |
| Cross-reactivity | Human, Rat, Mouse |
| Uniprot ID | Q9NQA5 |
| Note | Gene ID: 56302; UniProt: Q9NQA5; Chromosome: 7q34; Predicted MW: 82.6 kDa |
| Function | Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine. Required for normal Ca(2+) reabsorption in the kidney distal convoluted tubules (By similarity). The channel is activated by low internal calcium level and the current exhibits an inward rectification. A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay (By similarity). Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human TRPV5 Polyclonal Antibody |
| Target | TRPV5 |
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