Rabbit Anti-TRPC5 Polyclonal Antibody
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产品编号
PAV4139
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别名
transient receptor potential cation channel subfamily C member 5, PPP1R159, TRP5
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | transient receptor potential cation channel subfamily C member 5, PPP1R159, TRP5 |
| Catalog Number | PAV4139 |
| Product Description | Rabbit polyclonal antibody raised against human TRPC5 (Short transient receptor potential channel 5). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | TRPC5 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 离子通道 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene belongs to the transient receptor family. It encodes one of the seven mammalian TRPC (transient receptor potential channel) proteins. The encoded protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel. The protein is active alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4. It also interacts with multiple proteins including calmodulin, CABP1, enkurin, Na(+)-H+ exchange regulatory factor (NHERF ), interferon-induced GTP-binding protein (MX1), ring finger protein 24 (RNF24), and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1). [provided by RefSeq, May 2010] |
| Immunogen | This antibody was raised against from part region of human TRPC5 protein (UniProt: Q9UL62) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 7224 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈111.4 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 111.4 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q9UL62 |
| Note | Gene ID: 7224; UniProt: Q9UL62; Chromosome: Xq23; Predicted MW: 111.4 kDa |
| Function | Forms a receptor-activated non-selective calcium permeant cation channel. Mediates calcium-dependent phosphatidylserine externalization and apoptosis in neurons via its association with PLSCR1 (By similarity). Acts on distinct neuronal populations in the hypothalamus to regulate innate behaviors including feeding, anxiety (flight/fight/fear), socialization, and maternal care (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human TRPC5 Polyclonal Antibody |
| Target | TRPC5 |
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