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Rabbit Anti-SPB6/SERPINB6 Polyclonal Antibody
Rabbit Anti-SPB6/SERPINB6 Polyclonal Antibody

Rabbit Anti-SPB6/SERPINB6 Polyclonal Antibody

产品编号

PAV3777

别名

serpin family B member 6, CAP, DFNB91, MSTP057, PI-6, PI6, PTI, SPI3

目录价格

InquiryRMB

规格
  • 100ul
产品介绍
Aliasserpin family B member 6, CAP, DFNB91, MSTP057, PI-6, PI6, PTI, SPI3
Catalog NumberPAV3777
Product DescriptionRabbit polyclonal antibody raised against human SERPINB6 (Serpin B6). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular NameSERPINB6
SpeciesHuman, Mouse
HostRabbit
Size100ul
ClonityPolyclonal
Protein Family炎症/感染标志物
Concentration1 mg/ml
Purificationaffinity-chromatography
Formulationsupply in PBS containing 50% glycerol, and 0.02% sodium azide.
BackgroundThe protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2010]
ImmunogenThis antibody was raised against from part region of human SERPINB6 protein (UniProt: P35237)
ApplicationWB, ELISA
Recommended DilutionWB 1:500-2000 ELISA 1:5000-20000
Gene ID5269
TagUnconjugated
Cross-reactivityHuman, Mouse
Predicted Molecular Weight≈42.6 kDa
Storage ConditionStore at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping ConditionThis product is shipped on blue ice.
Molecular Weight42.6 kDa
Cross-reactivityHuman, Mouse
Uniprot IDP35237
NoteGene ID: 5269; UniProt: P35237; Chromosome: 6p25.2; Predicted MW: 42.6 kDa
FunctionMay be involved in the regulation of serine proteinases present in the brain or extravasated from the blood (By similarity). Inhibitor of cathepsin G, kallikrein-8 and thrombin. May play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss.
Product Declaration本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full NameRabbit Anti-Human SERPINB6 Polyclonal Antibody
TargetSERPINB6

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