Rabbit Anti-SPB6/SERPINB6 Polyclonal Antibody
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产品编号
PAV3777
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别名
serpin family B member 6, CAP, DFNB91, MSTP057, PI-6, PI6, PTI, SPI3
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目录价格
InquiryRMB
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规格
- 100ul
| Alias | serpin family B member 6, CAP, DFNB91, MSTP057, PI-6, PI6, PTI, SPI3 |
| Catalog Number | PAV3777 |
| Product Description | Rabbit polyclonal antibody raised against human SERPINB6 (Serpin B6). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | SERPINB6 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 炎症/感染标志物 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2010] |
| Immunogen | This antibody was raised against from part region of human SERPINB6 protein (UniProt: P35237) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 5269 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈42.6 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 42.6 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | P35237 |
| Note | Gene ID: 5269; UniProt: P35237; Chromosome: 6p25.2; Predicted MW: 42.6 kDa |
| Function | May be involved in the regulation of serine proteinases present in the brain or extravasated from the blood (By similarity). Inhibitor of cathepsin G, kallikrein-8 and thrombin. May play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human SERPINB6 Polyclonal Antibody |
| Target | SERPINB6 |
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