Rabbit Anti-SFRP4 Polyclonal Antibody
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产品编号
PAV3639
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别名
secreted frizzled related protein 4, FRP-4, FRPHE, FRZB-2, PYL, sFRP-4
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | secreted frizzled related protein 4, FRP-4, FRPHE, FRZB-2, PYL, sFRP-4 |
| Catalog Number | PAV3639 |
| Product Description | Rabbit polyclonal antibody raised against human SFRP4 (Secreted frizzled-related protein 4). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | SFRP4 |
| Species | Human, Rat, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 生长因子 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human SFRP4 protein (UniProt: Q6FHJ7) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 6424 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Rat, Mouse |
| Predicted Molecular Weight | ≈39.8 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 39.8 kDa |
| Cross-reactivity | Human, Rat, Mouse |
| Uniprot ID | Q6FHJ7 |
| Note | Gene ID: 6424; UniProt: Q6FHJ7; Chromosome: 7p14.1; Predicted MW: 39.8 kDa |
| Function | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types (By similarity). SFRP4 plays a role in bone morphogenesis. May also act as a regulator of adult uterine morphology and function. May also increase apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling (By similarity). Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human SFRP4 Polyclonal Antibody |
| Target | SFRP4 |
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