Rabbit Anti-NRG4 Polyclonal Antibody
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产品编号
PAV2604
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别名
neuregulin 4, HRG4
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | neuregulin 4, HRG4 |
| Catalog Number | PAV2604 |
| Product Description | Rabbit polyclonal antibody raised against human NRG4 (Pro-neuregulin-4, membrane-bound isoform). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | NRG4 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 生长因子 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The neuregulins, including NRG4, activate type-1 growth factor receptors (see EGFR; MIM 131550) to initiating cell-to-cell signaling through tyrosine phosphorylation (Harari et al., 1999 [PubMed 10348342]).[supplied by OMIM, Mar 2008] |
| Immunogen | This antibody was raised against from part region of human NRG4 protein (UniProt: Q8WWG1) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 145957 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈12.7 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 12.7 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q8WWG1 |
| Note | Gene ID: 145957; UniProt: Q8WWG1; Chromosome: 15q24.2; Predicted MW: 12.7 kDa |
| Function | Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human NRG4 Polyclonal Antibody |
| Target | NRG4 |
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