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Rabbit Anti-TA2R/TBXA2R Polyclonal Antibody
Rabbit Anti-TA2R/TBXA2R Polyclonal Antibody

Rabbit Anti-TA2R/TBXA2R Polyclonal Antibody

产品编号

PAV3931

别名

thromboxane A2 receptor, BDPLT13, TXA2-R

目录价格

InquiryRMB

规格
  • 100ul
产品介绍
Aliasthromboxane A2 receptor, BDPLT13, TXA2-R
Catalog NumberPAV3931
Product DescriptionRabbit polyclonal antibody raised against human TBXA2R (Thromboxane A2 receptor). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular NameTBXA2R
SpeciesHuman, Rat, Mouse
HostRabbit
Size100ul
ClonityPolyclonal
Protein FamilyG蛋白偶联受体
Concentration1 mg/ml
Purificationaffinity-chromatography
Formulationsupply in PBS containing 50% glycerol, and 0.02% sodium azide.
BackgroundThis gene encodes a member of the G protein-coupled receptor family. The protein interacts with thromboxane A2 to induce platelet aggregation and regulate hemostasis. A mutation in this gene results in a bleeding disorder. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
ImmunogenThis antibody was raised against from part region of human TBXA2R protein (UniProt: P21731)
ApplicationWB, ELISA
Recommended DilutionWB 1:500-2000 ELISA 1:5000-20000
Gene ID6915
TagUnconjugated
Cross-reactivityHuman, Rat, Mouse
Predicted Molecular Weight≈37.4 kDa
Storage ConditionStore at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping ConditionThis product is shipped on blue ice.
Molecular Weight37.4 kDa
Cross-reactivityHuman, Rat, Mouse
Uniprot IDP21731
NoteGene ID: 6915; UniProt: P21731; Chromosome: 19p13.3; Predicted MW: 37.4 kDa
FunctionReceptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C.; FUNCTION: [Isoform 1]: Activates adenylyl cyclase.; FUNCTION: [Isoform 2]: Inhibits adenylyl cyclase.
Product Declaration本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full NameRabbit Anti-Human TBXA2R Polyclonal Antibody
TargetTBXA2R

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