Rabbit Anti-PACR/ADCYAP1R1 Polyclonal Antibody
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产品编号
PAV2913
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别名
ADCYAP receptor type I, PAC1, PAC1R, PACAPR, PACAPRI
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | ADCYAP receptor type I, PAC1, PAC1R, PACAPR, PACAPRI |
| Catalog Number | PAV2913 |
| Product Description | Rabbit polyclonal antibody raised against human ADCYAP1R1 (Pituitary adenylate cyclase-activating polypeptide type I receptor). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | ADCYAP1R1 |
| Species | Human, Rat, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | G蛋白偶联受体 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2010] |
| Immunogen | This antibody was raised against from part region of human ADCYAP1R1 protein (UniProt: P41586) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 117 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Rat, Mouse |
| Predicted Molecular Weight | ≈53.3 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 53.3 kDa |
| Cross-reactivity | Human, Rat, Mouse |
| Uniprot ID | P41586 |
| Note | Gene ID: 117; UniProt: P41586; Chromosome: 7p14.3; Predicted MW: 53.3 kDa |
| Function | G protein-coupled receptor activated by the neuropeptide pituitary adenylate cyclase-activating polypeptide (ADCYAP1/PACAP). Binds both PACAP27 and PACAP38 bioactive peptides. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. Activates cAMP-dependent pathway. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human ADCYAP1R1 Polyclonal Antibody |
| Target | ADCYAP1R1 |
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