Rabbit Anti-SLUR1/SLURP1 Polyclonal Antibody
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产品编号
PAV3712
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别名
secreted LY6/PLAUR domain containing 1, ANUP, ARS, ArsB, LY6-MT, LY6LS, MDM
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | secreted LY6/PLAUR domain containing 1, ANUP, ARS, ArsB, LY6-MT, LY6LS, MDM |
| Catalog Number | PAV3712 |
| Product Description | Rabbit polyclonal antibody raised against human SLURP1 (Secreted Ly-6/uPAR-related protein 1-81/S)). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | SLURP1 |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 细胞外基质 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The protein encoded by this gene is a member of the Ly6/uPAR family but lacks a GPI-anchoring signal sequence. It is thought that this secreted protein contains antitumor activity. Mutations in this gene have been associated with Mal de Meleda, a rare autosomal recessive skin disorder. This gene maps to the same chromosomal region as several members of the Ly6/uPAR family of glycoprotein receptors. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human SLURP1 protein (UniProt: P55000) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 57152 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈11.2 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 11.2 kDa |
| Cross-reactivity | Human |
| Uniprot ID | P55000 |
| Note | Gene ID: 57152; UniProt: P55000; Chromosome: 8q24.3; Predicted MW: 11.2 kDa |
| Function | Has an antitumor activity. Was found to be a marker of late differentiation of the skin. Implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin. In vitro down-regulates keratinocyte proliferation; the function may involve the proposed role as modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-7-dependent nAChR currents in an allosteric manner. In T cells may be involved in regulation of intracellular Ca(2+) signaling. Seems to have an immunomodulatory function in the cornea (By similarity). The function may implicate a possible role as a scavenger receptor for PLAU thereby blocking PLAU-dependent functions of PLAUR such as in cell migration and proliferation. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human SLURP1 Polyclonal Antibody |
| Target | SLURP1 |
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