Rabbit Anti-PLOD2 Polyclonal Antibody
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产品编号
PAV3078
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别名
procollagen-lysine,2-oxoglutarate 5-dioxygenase 2, BRKS2, LH2, TLH
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | procollagen-lysine,2-oxoglutarate 5-dioxygenase 2, BRKS2, LH2, TLH |
| Catalog Number | PAV3078 |
| Product Description | Rabbit polyclonal antibody raised against human PLOD2 (Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | PLOD2 |
| Species | Human, Rat, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 细胞外基质 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human PLOD2 protein (UniProt: O00469) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 5352 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Rat, Mouse |
| Predicted Molecular Weight | ≈84.7 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 84.7 kDa |
| Cross-reactivity | Human, Rat, Mouse |
| Uniprot ID | O00469 |
| Note | Gene ID: 5352; UniProt: O00469; Chromosome: 3q24; Predicted MW: 84.7 kDa |
| Function | Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human PLOD2 Polyclonal Antibody |
| Target | PLOD2 |
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