Rabbit Anti-PRDM5 Polyclonal Antibody
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产品编号
PAV3149
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别名
PR/SET domain 5, BCS2, PFM2
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | PR/SET domain 5, BCS2, PFM2 |
| Catalog Number | PAV3149 |
| Product Description | Rabbit polyclonal antibody raised against human PRDM5 (PR domain zinc finger protein 5). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | PRDM5 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 表观修饰酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The protein encoded by this gene is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human PRDM5 protein (UniProt: Q9NQX1) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 11107 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈73.1 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 73.1 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q9NQX1 |
| Note | Gene ID: 11107; UniProt: Q9NQX1; Chromosome: 4q27; Predicted MW: 73.1 kDa |
| Function | Sequence-specific DNA-binding transcription factor. Represses transcription at least in part by recruitment of the histone methyltransferase EHMT2/G9A and histone deacetylases such as HDAC1. Regulates hematopoiesis-associated protein-coding and microRNA (miRNA) genes. May regulate the expression of proteins involved in extracellular matrix development and maintenance, including fibrillar collagens, such as COL4A1 and COL11A1, connective tissue components, such as HAPLN1, and molecules regulating cell migration and adhesion, including EDIL3 and TGFB2. May cause G2/M arrest and apoptosis in cancer cells. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human PRDM5 Polyclonal Antibody |
| Target | PRDM5 |
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