Rabbit Anti-NSD3 Polyclonal Antibody
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产品编号
PAV2611
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别名
nuclear receptor binding SET domain protein 3, KMT3F, KMT3G, WHISTLE, WHSC1L1, pp14328
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | nuclear receptor binding SET domain protein 3, KMT3F, KMT3G, WHISTLE, WHSC1L1, pp14328 |
| Catalog Number | PAV2611 |
| Product Description | Rabbit polyclonal antibody raised against human NSD3 (Histone-lysine N-methyltransferase NSD3). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | NSD3 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 表观修饰酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. This protein methylates histone H3 at lysine residues 4 and 27, which represses gene transcription. Two alternatively spliced variants have been described. [provided by RefSeq, May 2015] |
| Immunogen | This antibody was raised against from part region of human NSD3 protein (UniProt: Q9BZ95) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 54904 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈161.6 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 161.6 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q9BZ95 |
| Note | Gene ID: 54904; UniProt: Q9BZ95; Chromosome: 8p11.23; Predicted MW: 161.6 kDa |
| Function | Histone methyltransferase. Preferentially dimethylates 'Lys-4' and 'Lys-27' of histone H3 forming H3K4me2 and H3K27me2. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human NSD3 Polyclonal Antibody |
| Target | NSD3 |
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