Rabbit Anti-NP1L1/NAP1L1 Polyclonal Antibody
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产品编号
PAV2565
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别名
nucleosome assembly protein 1 like 1, NAP1, NAP1L, NRP
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | nucleosome assembly protein 1 like 1, NAP1, NAP1L, NRP |
| Catalog Number | PAV2565 |
| Product Description | Rabbit polyclonal antibody raised against human NAP1L1 (Nucleosome assembly protein 1-like 1). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | NAP1L1 |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 表观修饰酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a member of the nucleosome assembly protein (NAP) family. This protein participates in DNA replication and may play a role in modulating chromatin formation and contribute to the regulation of cell proliferation. Alternative splicing results in multiple transcript variants encoding different isoforms; however, not all have been fully described. [provided by RefSeq, Apr 2015] |
| Immunogen | This antibody was raised against from part region of human NAP1L1 protein (UniProt: P55209) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 4673 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈45.4 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 45.4 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | P55209 |
| Note | Gene ID: 4673; UniProt: P55209; Chromosome: 12q21.2; Predicted MW: 45.4 kDa |
| Function | Histone chaperone that plays a role in the nuclear import of H2A-H2B and nucleosome assembly. Also participates in several important DNA repair mechanisms: greatly enhances ERCC6-mediated chromatin remodeling which is essential for transcription-coupled nucleotide excision DNA repair. Also stimulates homologous recombination (HR) by RAD51 and RAD54 which is essential in mitotic DNA double strand break (DSB) repair. Plays a key role in the regulation of embryonic neurogenesis (By similarity). Promotes the proliferation of neural progenitors and inhibits neuronal differentiation during cortical development (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human NAP1L1 Polyclonal Antibody |
| Target | NAP1L1 |
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