Rabbit Anti-NASP Polyclonal Antibody
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产品编号
PAV2455
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别名
nuclear autoantigenic sperm protein, FLB7527, HMDRA1, PRO1999
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | nuclear autoantigenic sperm protein, FLB7527, HMDRA1, PRO1999 |
| Catalog Number | PAV2455 |
| Product Description | Rabbit polyclonal antibody raised against human NASP (Nuclear autoantigenic sperm protein). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | NASP |
| Species | Human, Rat, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 表观修饰酶 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a H1 histone binding protein that is involved in transporting histones into the nucleus of dividing cells. Multiple isoforms are encoded by transcript variants of this gene. The somatic form is expressed in all mitotic cells, is localized to the nucleus, and is coupled to the cell cycle. The testicular form is expressed in embryonic tissues, tumor cells, and the testis. In male germ cells, this protein is localized to the cytoplasm of primary spermatocytes, the nucleus of spermatids, and the periacrosomal region of mature spermatozoa. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human NASP protein (UniProt: P49321) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 4678 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Rat, Mouse |
| Predicted Molecular Weight | ≈85.2 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 85.2 kDa |
| Cross-reactivity | Human, Rat, Mouse |
| Uniprot ID | P49321 |
| Note | Gene ID: 4678; UniProt: P49321; Chromosome: 1p34.1; Predicted MW: 85.2 kDa |
| Function | Component of the histone chaperone network. Binds and stabilizes histone H3-H4 not bound to chromatin to maintain a soluble reservoir and modulate degradation by chaperone-mediated autophagy. Required for DNA replication, normal cell cycle progression and cell proliferation. Forms a cytoplasmic complex with HSP90 and H1 linker histones and stimulates HSP90 ATPase activity. NASP and H1 histone are subsequently released from the complex and translocate to the nucleus where the histone is released for binding to DNA.; FUNCTION: [Isoform 1]: Stabilizes soluble histone H3-H4.; FUNCTION: [Isoform 2]: Stabilizes soluble histone H3-H4. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human NASP Polyclonal Antibody |
| Target | NASP |
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