Rabbit Anti-RMI2 Polyclonal Antibody
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产品编号
PAV3413
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别名
RecQ mediated genome instability 2, BLAP18, C16orf75
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | RecQ mediated genome instability 2, BLAP18, C16orf75 |
| Catalog Number | PAV3413 |
| Product Description | Rabbit polyclonal antibody raised against human RMI2 (RecQ-mediated genome instability protein 2). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | RMI2 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | DNA损伤修复 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | RMI2 is a component of the BLM (RECQL3; MIM 604610) complex, which plays a role in homologous recombination-dependent DNA repair and is essential for genome stability (Xu et al., 2008 [PubMed 18923082]).[supplied by OMIM, Nov 2008] |
| Immunogen | This antibody was raised against from part region of human RMI2 protein (UniProt: Q96E14) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 116028 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈15.9 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 15.9 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q96E14 |
| Note | Gene ID: 116028; UniProt: Q96E14; Chromosome: 16p13.13; Predicted MW: 15.9 kDa |
| Function | Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates. It is required to regulate sister chromatid segregation and to limit DNA crossover. Essential for the stability, localization, and function of BLM, TOP3A, and complexes containing BLM. In the RMI complex, it is required to target BLM to chromatin and stress-induced nuclear foci and mitotic phosphorylation of BLM. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human RMI2 Polyclonal Antibody |
| Target | RMI2 |
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