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Rabbit Anti-RFC5 Polyclonal Antibody
Rabbit Anti-RFC5 Polyclonal Antibody

Rabbit Anti-RFC5 Polyclonal Antibody

产品编号

PAV3327

别名

replication factor C subunit 5, RFC36

目录价格

InquiryRMB

规格
  • 100ul
产品介绍
Aliasreplication factor C subunit 5, RFC36
Catalog NumberPAV3327
Product DescriptionRabbit polyclonal antibody raised against human RFC5 (Replication factor C subunit 5). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular NameRFC5
SpeciesHuman, Mouse
HostRabbit
Size100ul
ClonityPolyclonal
Protein FamilyDNA损伤修复
Concentration1 mg/ml
Purificationaffinity-chromatography
Formulationsupply in PBS containing 50% glycerol, and 0.02% sodium azide.
BackgroundThis gene encodes the smallest subunit of the replication factor C complex, which consists of five distinct subunits (140, 40, 38, 37, and 36 kDa) and is required for DNA replication. This subunit interacts with the C-terminal region of proliferating cell nuclear antigen and is required to open and load proliferating cell nuclear antigen onto DNA during S phase. It is a member of the AAA+ (ATPases associated with various cellular activities) ATPase family and forms a core complex with the 38 and 40 kDa subunits that possesses DNA-dependent ATPase activity. A related pseudogene has been identified on chromosome 9. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]
ImmunogenThis antibody was raised against from part region of human RFC5 protein (UniProt: P40937)
ApplicationWB, ELISA
Recommended DilutionWB 1:500-2000 ELISA 1:5000-20000
Gene ID5985
TagUnconjugated
Cross-reactivityHuman, Mouse
Predicted Molecular Weight≈38.5 kDa
Storage ConditionStore at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping ConditionThis product is shipped on blue ice.
Molecular Weight38.5 kDa
Cross-reactivityHuman, Mouse
Uniprot IDP40937
NoteGene ID: 5985; UniProt: P40937; Chromosome: 12q24.23; Predicted MW: 38.5 kDa
FunctionSubunit of the replication factor C (RFC) complex which acts during elongation of primed DNA templates by DNA polymerases delta and epsilon, and is necessary for ATP-dependent loading of proliferating cell nuclear antigen (PCNA) onto primed DNA.
Product Declaration本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full NameRabbit Anti-Human RFC5 Polyclonal Antibody
TargetRFC5

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