Rabbit Anti-RECQ4/RECQL4 Polyclonal Antibody
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产品编号
PAV3312
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别名
RecQ like helicase 4, RECQ4
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | RecQ like helicase 4, RECQ4 |
| Catalog Number | PAV3312 |
| Product Description | Rabbit polyclonal antibody raised against human RECQL4 (ATP-dependent DNA helicase Q4). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | RECQL4 |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | DNA损伤修复 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The protein encoded by this gene is a DNA helicase that belongs to the RecQ helicase family. DNA helicases unwind double-stranded DNA into single-stranded DNAs and may modulate chromosome segregation. This gene is predominantly expressed in thymus and testis. Mutations in this gene are associated with Rothmund-Thomson, RAPADILINO and Baller-Gerold syndromes. [provided by RefSeq, Jan 2010] |
| Immunogen | This antibody was raised against from part region of human RECQL4 protein (UniProt: O94761) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 9401 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈133.1 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 133.1 kDa |
| Cross-reactivity | Human |
| Uniprot ID | O94761 |
| Note | Gene ID: 9401; UniProt: O94761; Chromosome: 8q24.3; Predicted MW: 133.1 kDa |
| Function | An ATP-dependent DNA helicase which unwinds dsDNA with a 3'-overhang in a 3'-5' direction. Does not unwind more than 18 bp of dsDNA. May modulate chromosome segregation. The N-terminal domain (residues 1-54) binds DNA Y-shaped DNA better than ss- or dsDNA. The core helicase domain binds ssDNA. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human RECQL4 Polyclonal Antibody |
| Target | RECQL4 |
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